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靶向治疗

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Targeted cancer therapies are treatments that target specific characteristics of cancer cells, such as a protein that allows the cancer cells to grow in a rapid or abnormal way. Targeted therapies are generally less likely than chemotherapy to harm normal, healthy cells. Some targeted therapies are antibodies that work like the antibodies made naturally by our immune systems. These types of targeted therapies are sometimes called immune targeted therapies.

孕妇不应该得到针对性治疗。已经做了一些调查表明,有针对性的治疗不是怀孕期间的安全。访问Treatment for Breast Cancer During Pregnancy页面了解更多信息。

这些都是有针对性的治疗医生使用治疗乳腺癌:

Afinitor的
AFINITOR(化学名:依维莫司)是mTOR抑制剂。对已通过得到他们所需要的能量停止癌细胞停止响应瑞宁或Femara的激素受体阳性乳腺癌Afinitor的作品。
Avastin
阿瓦斯汀(化学名:贝伐单抗)是用于关闭标签的治疗某些晚期或转移性乳腺癌的血管生长抑制剂。阿瓦斯丁通过阻断新血管的生长,癌细胞依赖于生长和功能。
Enhertu
Enhertu(化学名:FAM-曲妥珠单抗deruxtecan-nxki)是三个部分组成靶向治疗:抗HER2药,化疗药的化合物,并且该链接的化疗和抗HER2药物一起。Enhertu工作对已与两个或更多的抗HER2疗法治疗不能切除(不能用手术去除的)和转移性HER2阳性乳腺癌。
赫赛汀
赫赛汀(chemical name: trastuzumab) is a HER2 inhibitor targeted therapy. Herceptin works against HER2-positive breast cancers by blocking the ability of the cancer cells to receive chemical signals that tell the cells to grow.
Ibrance
Ibrance(化学名:palbociclib)是CDK4/6 inhibitor。Ibrance作品针对晚期或转移性,激素 - 受体阳性,HER2阴性乳腺癌通过分裂和生长停止癌细胞。
Kadcyla
Kadcyla (chemical name: T-DM1 or ado-trastuzumab emtansine) is a combination of Herceptin and the chemotherapy medicine emtansine. Kadcyla was designed to deliver emtansine to cancer cells in a targeted way by attaching emtansine to Herceptin. Herceptin then carries emtansine to the HER2-positive cancer cells.
Kisqali
Kisqali(化学名:ribociclib)是CDK4/6 inhibitorlike Ibrance. Kisqali works against advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer by stopping cancer cells from dividing and growing.
Lynparza
Lynparza(化学名:奥拉帕尼)是一种PARP抑制剂。在健康和癌症细胞PARP酶修复DNA损伤。Lynparza工作对转移性HER2阴性乳腺癌与BRCA1orBRCA2通过使这些癌细胞对修复DNA损伤很难突变。
Nerlynx
Nerlynx (chemical name: neratinib) is an irreversible pan-HER inhibitor. Nerlynx works against HER2-positive breast cancer by blocking the cancer cells’ ability to receive growth signals.
Perjeta
Perjeta(化学名:帕妥珠单抗)是HER2抑制剂靶向治疗,赫赛汀一样。Perjeta通过阻断癌细胞接收生长信号的能力工作针对HER2阳性乳腺癌。
Piqray
Piqray(化学名:alpelisib)是PI3K抑制剂。Piqray被用于治疗晚期阶段或转移性激素受体阳性,HER2阴性乳腺癌与PIK3CA已经与绝经后妇女和男性荷尔蒙疗法治疗后生长突变。
Talzenna
Talzenna(化学名:talazoparib)是一种PARP抑制剂,如Lynparza。Talzenna使用带有治疗局部晚期或转移性HER2阴性乳腺癌BRCA1orBRCA2通过使这些癌细胞对修复DNA损伤很难突变。
Trodelvy
Trodelvy (chemical name: sacituzumab govitecan-hziy) is an antibody-drug conjugate immune targeted therapy made up of: a monoclonal antibody that targets the Trop-2 protein, a chemotherapy medicine, and a compound that links the monoclonal antibody and the chemotherapy. Trodelvy is used to treat metastatic triple-negative breast cancer that has previously been treated with at least two therapies.
Tukysa
Tukysa(化学名:tucatinib)是酪氨酸激酶抑制剂。酪氨酸激酶酶,帮助控制细胞如何生长和分裂,其它功能。如果酶过于活跃或者如果电池有太多的酶,它可以使细胞失控生长。通过阻断的特定区域Tukysa治疗某些晚期HER2阳性乳腺癌HER2基因在肿瘤细胞中,这阻止了细胞生长和扩散。
的Tykerb
Tykerb(化学名称:拉帕替尼)是一种HER2 inhibitor targeted therapy, like Herceptin and Perjeta. Tykerb works against HER2-positive breast cancers by blocking certain proteins that can cause uncontrolled cell growth.
Verzenio
Verzenio(化学名:abemaciclib)是CDK4/6 inhibitor, like Ibrance and Kisqali. Verzenio works against advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer by stopping cancer cells from dividing and growing.

Reviewed by:

布赖恩·沃伊切霍夫斯基,医学博士,肿瘤内科,凿槽工具,梯形校正卫生系统,费城,PA;金宝搏专属安卓APPBreastcancer.org医疗顾问


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